These guidelines cover the design and implementation of integrated monitoring and surveillance programme(s) for foodborne AMR and AMU along the food chain and the food production environment. Although these guidelines do not cover the design and implementation of monitoring and surveillance of AMR and AMU in humans, an integrated programme within the context of overall risk management of AMR (One Health approach) may be informed by data, trends, methodology and epidemiology regarding AMR and AMU in humans. The microorganisms covered by these guidelines are foodborne pathogens of public health relevance and indicator bacteria. Antimicrobials used as biocides including disinfectants, are excluded from the scope of these guidelines.